The scientific research by Dr. Marco Lombardo is focused on optics, corneal biomechanics, biocompatibility of intraocular lens and innnovation technology in Ophthalmology.  Dr. Lombardo is principal investigator in various assorted clinical and experimental projects aimed at optimizing the outcome of corneal transplantation surgery, using femtosecond laser platform, and keratoconus treatment, by developing new methods of cross-linking.

Dr. Lombardo is specialized into the application of nanotechnology techniques in Ophthalmology, such as Atomic Force Microscopy. One of his main interest is devoted to the development of Adaptive Optics retinal camera for the early detection of retinal diseases. He is currently the principal investigator of the unique clinical research study on Adaptive Optics for Vision Science in Italy.